Officials spoke about the sanctions on the condition of anonymity because they were not authorized to discuss pending actions.
The final number of Russians facing punitive action remains fluid, the U.S. officials said, but is expected to include at least a half-dozen people under sanction powers given to the president by Congress.
In recent weeks, Trump’s national security advisers have pushed for more sanctions after the poisoning of a former Russian spy in England, interference in the U.S. 2016 elections and a cyberattack described as the most destructive and costly in history.
The United States is expected to target individuals on a list of influential Russian political and business leaders that the Treasury Department released in January, officials said.
The United States could also impose sanctions based on powers granted by Congress to target anyone conducting significant business with Russian intelligence and defense sectors.
"If they do something tough like this, it may go some distance in reassuring angry members of Congress and the public who are looking at the midterms and wondering if this administration is focused on the Russian threat and taking moves to address it," said Liz Rosenberg, a former Treasury official who is at the Center for a New American Security.
The pending move from Treasury comes as the Trump administration takes an increasingly tough posture toward Moscow at the urging of the president’s senior aides and top U.S. allies.
As reported, Russian ex-spy Sergei Skripal, 66, and daughter Yulia Skripal, 33, remain critically ill in hospital, after they were found unconscious on a bench in the Wiltshire city on March 4. The UK government says they were poisoned with a nerve agent of a type developed by Russia called Novichok and PM Theresa May said she believed Moscow was "culpable."
UK expelled 23 Russian diplomats as part of a "full and robust" response – prompting Russia's Foreign Minister Sergei Lavrov to say it will "certainly" expel British diplomats in response.
On March 16, Nato Secretary General Jens Stoltenberg said the alliance had "no reason to doubt the findings and assessments by the British government" which suggested Russian responsibility. He said the "UK is not alone" and Nato allies gave "strong political support" to Britain, following a joint statement from the US, France and Germany backing Mrs May's government and a pledge of support from Australia.
British Foreign Minister Boris Johnson said that the U.K.'s government believes that it was likely Putin's decision to direct the use of a nerve agent on the streets of the U.K.
On March 26, U.S. President Donald Trump ordered the expulsion of 60 Russians from the United States, including 12 people identified as Russian intelligence officers who have been stationed at the United Nations in New York.